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Themed collection Coronavirus articles - free to access collection

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Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

大众创业,万众创新
For all of these films, Ms. Swinton used the same tooth-designing specialist, Chris Lyons of the company Fangs F/X in London. His work has led him to designing all manner of teeth, including gold fangs fitted for a Doberman used in a Kanye West music video.

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

2011年,她的妈妈梅丽莎(Melissa)报名参加Lifetime频道的真人秀节目《Dance Moms》。
“Who’s going to pay for that?” said Marc J. Luxemburg, the president of the Council of New York Cooperatives and Condominiums. “This has a real-world cost for many buildings.”

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

From the themed collection: 合肥公布租房补贴申请指南
Open Access Perspective

Soft matter science and the COVID-19 pandemic

很多企业家已经有了Gmail邮箱地址,但并不是每个企业家都知道谷歌文档(Google Docs)的强大用途。利用谷歌文档,你可以即时创建可分享的文档、工作表和演示文稿。更重要的是,团队的每名成员都可以通过网络更新这些文档。好好使用它的“修订”功能吧!

Graphical abstract: Soft matter science and the COVID-19 pandemic
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

《战地神探》(Foyle’s War),acorn.tv,2月2日播出。去年流媒体服务网络Acorn TV放完了《大侦探波洛》(Agatha Christie’s Poirot)的最后三集,如今又带来另一部传统英国推理剧,这部超级剧集在英国已经拍到第九季,在美国还是首次播出。迈克尔·基臣(Michael Kitchen)在剧中饰演克里斯托弗·弗伊(Christopher Foyle),一位可敬而又狡黠的侦探,这部剧多年来从一部“二战”后方警探剧演变成勒卡雷(le Carré)式的冷战惊悚剧。新的几集中有纽伦堡审判以及英国在巴勒斯坦所扮演的角色。

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

Faber laughs at Bernanke's remark that the economy would be strong enough later this year so he could take his foot off the gas, that is begin 'tapering, or scaling back it's stimulative quantitative easing (QE) program later this year.' Yes, laughed.
移动端取代网页端。
在实验中,参与者们被要求回忆一些他们在实验开始的时候看到的图片,其中,一半参与者在回忆之前进行了举重训练,另一半参与者没有进行这样的高强度活动。他们发现,参与了举重训练的人在记忆能力上有所提高。这项研究实现了运动研究上的独辟蹊径,其他研究的研究对象多是对有氧运动本身,研究时间跨度长达数,但是这项研究的研究对象却是人类记忆,在研究时也仅仅是要求参与者们花一点时间举重而已。研究人员证明了其实提升记忆力并不需要数个小时的锻炼。下次再有谁让你去举重或者去健身馆锻炼的话,你大概会想感谢他一番的吧?
12月8日,佳士得(Christie’s)的双年夜间拍卖会仅拍得650万英镑(含佣金),约合970万美元,而最低预估价为1270万英镑。45件作品中有19件流拍,比例达42%,包括两幅估价最高的作品——阿尔布雷特·丢勒(Albrecht Dürer)的学生汉斯·霍夫曼(Hans Hoffmann)1582年创作的水彩习作——丛林中的野兔,还有弗朗西斯科·瓜尔迪(Francesco Guardi)在18世纪70年代创作的描绘威尼斯圣乔治马焦雷岛美景的油画,这两幅画的最低估价分别是400万英镑和150万英镑。

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Perspective

Trends and targets in antiviral phototherapy

而诺贝尔物理学奖则颁给了三位生于英国、目前正在美国工作的科学家,肯定了他们对极端状态下物质的特异属性所做的原子级研究。
认真思考一下:未来的经历能提高你的知识和技能吗?它是否会让你接触到新的观点,认识不同的人?(这些都是支持你对机会说“Yes”的好理由!)你需要为了管理团队或与经验更加丰富的同事共事而培养新技巧吗?如果答案是肯定的,那就接受这种挑战,走出你的舒适区。
但是航空公司在冬季假日期间的经营更加困难。2012年,大约有30%的冬季假日航班延误,高于2011年和2010年的航班延误率。你可以通过美国交通运输部的网站查看假日航班的统计数据。
INDOORS: The two-story stucco contemporary was built in 2005. The interior is an airy open space; white walls contrast with red tile floors. Walls of sliding glass doors face live oaks and marshland on the Wilmington River.

Graphical abstract: Trends and targets in antiviral phototherapy
From the themed collection: 瓷砖企业在固步自封中丧失主动权
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

v. 燃烧,面红,爆发

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

单词extend 联想记忆:

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

The host list of 2014 Spring Festival Gala, including Zhu Jun, Dong Qing, Bi Fujian, Li Sisi and Zhang Guoli, are released on Wednesday. Chinese film actor and director Zhang Guoli will host the annual gala of China Central Television (CCTV) for the first time.
The country has rolled out measures to promote new-energy vehicles, including tax exemptions, subsidies for car purchases and a requirement for government departments to buy more new-energy cars.

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

Tsinghua University and Peking University are ranked in 14th and 17th place respectively -- the same positions they held in last year's rankings.
For now, D'Aloisio isn't touching the money. 'I'm too young to appreciate the value of it,' he insists. 'I don't have a mortgage, I'm 17. To me, a hundred pounds is a lot. Take that as a benchmark.' Though he's not allowed to comment on Summly's sale price, when pressed he allows that he might one day like to deploy his newfound riches as an angel investor. No one around him seems to think there's a danger that the money will ruin him or that he'll be tempted to spend the rest of his life dissipating on a beach. 'He's pretty well grounded. You wouldn't believe how frugal he is,' says Diane. 'He's got a great engine,' says Lou. 'He won't stop at this.'

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
From the themed collection: 卫浴洁具行业的发展趋势与机会
Open Access Review Article

Diagnostic technologies for COVID-19: a review

6. 《火星救援》(The Martian)。在布满红色岩石的山坡与丘陵之间,雷利·斯科特(Ridley Scott)这部非常令人满意的太空西部片既源自一个历史悠久的类型,也源自他的殿堂级遗产。
['spekju.l?tiv]

Graphical abstract: Diagnostic technologies for COVID-19: a review
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

理查三世的遗骨将在当地教堂被正式重新埋葬。他一直被视为英国历史上最残酷的暴君之一,威廉-莎士比亚将其刻画为“驼背的暴君”。
小说作者安东尼·赫洛维兹(Anthony Horowitz)透露,新书《Trigger Mortis》为现代读者作了改动,包含反对吸烟的信息,而且首次有一位“直言不讳”的同性恋朋友出场。
金维刚补充说道:“去年前三季度职工平均工资增长幅度大致在6.3%,而我国2016年GDP增速则为6.7%。这两项都要比之前一年有所下降。”
高盛将大派红包,饱受各方抨击一个月,然后静悄悄地干回自己的老本行--挣钱。

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

Jonathan Glazer’s Under the Skin is a film about a beautiful, scary alien that is itself beautiful and scary and alien: it’s an entirely extraordinary, outrageously sensual film that Glazer’s previous excellent work had really only hinted at, partially and indistinctly. His Sexy Beast (2000) was a visually accomplished, exciting and intelligent crime thriller that was way ahead of the woeful mockney-geezer mode of the time. Birth (2004) had Kubrickian ingenuity and chill, with some remarkable moments; it was a movie that deserves cult-classic status but has yet to achieve it. Then a decade went by, and it seemed that Glazer might be a stylist for whom a sustained cinema career would perhaps not be achievable (and heaven knows, it can happen to the most talented).

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
From the themed collection: 内蒙古商品房待售面积持续下降
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

Following the devaluation in mid-August, the renminbi rallied in September and October. Devaluation resumed in November, however, and the renminbi closed at its weakest level in three months at 6.4082 to the dollar yesterday. “Since October many countries around China have experienced some capital outflow, and China has had its share,” said Xie Yaxuan, an economist at China Merchants Securities in Shenzhen. “The strengthening dollar is bound to cause some repositioning into dollar assets.”
中央财政拿了1000亿元专项资金用于员工转岗安置,并且要求地方政府配套。

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

该研究基于全国3095份应届毕业生调查问卷和1661份雇主调查问卷。

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

The report said there were now 594 dollar billionaires in China, putting China ahead of the United States' 535. However, none of China's super-rich make it into the global top 20.

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

Bolder lawyers will start working with more “sci-fi” programs that claim to predict the outcomes of legal disputes before they have reached court, by analysing similar cases and past rulings, opposition tactics and win/lose statistics, the success rates of certain lawyers before certain judges, and so on.
……睡着了。
Hurricane Harvey
Hugo Boss, Chevrolet and Kleenex dropped off the list, the report said.

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
Review Article

Influenza neuraminidase: A druggable target for natural products

今年1月3日春节假期车票开售以来,约有2.8亿张火车票是在12306网站上售出的。
This technology previously existed for arms, but legs are rather more complicated. And since a misread signal can send you jumping off a bridge or in front of a moving car, thought-controlled legs need more stringent programming than equivalent arms. As one of the researchers delicately put it, “If you're using a bionic arm and it misbehaves, the elbow may move slightly. If the prosthetic leg misbehaves . . . that could be quite a safety issue.”
5. Google Webmaster Tools.
200911/90348.shtml
Writing for a Comedy Series: Aziz Ansari and Alan Yang, “Master of None” (“Parents”)

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

15. An Amazing Coincidence One of the studios with the most on-screen diversity — it released “Trainwreck” and “Straight Outta Compton” (if also “Ted 2”) — and with the most female directors is Universal, which, as of early December, had gobbled up almost 24 percent of the year’s market share.
Up to 10,000 copies of the film - a comedy about a fictional CIA plot to assassinate North Korean leader Kim Jong-Un - and 500,000 political leaflets are scheduled for a balloon-launch around 26 March.

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Critical Review

The role of biosensors in the detection of emerging infectious diseases

It was the first "real" James Bond song (again, the first two films only opened with orchestral music), and it's still the best. Shirley Bassey got an opportunity to sing her soul out and she accepted the challenge with obvious pleasure. This is a song that makes the villain Auric Goldfinger seem a lot more threatening (and attractive) than he actually is, but that's part of the miracle of Bassey's work here. It's proud and heroic and enticing and it's kind of a lie, but who cares? The music is pure James Bond, the lyrics are pure machismo, and the performance is perfect.

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

Graduates of Tsinghua University make more money, on average, than those from any other college in China, results of a recent survey showed.

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

Dreamworks Animation
Will the Democrats take back the majority in the midterm election in the US House of Representatives
当然我们不可能列举出所有女性,这个榜单的评选范围仅限于那些名气较大的女星。下面就让我们来见识一下这些热辣美女吧。
As a result, his position on the Forbes' ranking dropped 220 spots, leaving him tied with 19 others as the 544th richest person in the world.

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

Britney, YOU drive me crazy for appearing on Loose Women smacking gum like it's 1998 as the panel interrogate you.
in进入,stitute站,建立-站进去;进入建立的状态-创立
特朗普说道:"她唯一能做的就是打女人牌。我愿意看到美国能有一位女主席,但希拉里绝对是错误人选,她简直就是一场灾难。"
Kay说我很一直很吃惊因为很多人都会告诉他们的同事找工作的事。这是你做的最糟糕的事情之一。理论上说你不能告诉任何同事,但是有时你不得不告诉他们因为想得到他们的引荐。如果那样的话Kay说,你得挑一些值得信任的人,他们不会背后秘密异议也不会口误说出去。

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

But the economic base for these capabilities is steadily declining.
China does not want to resort to yuan depreciation to boost exports as that would dampen the restructuring and upgrading of the corporate sector.

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

We need to ensure that our consumers will have access to good options, benefit from such consumption, and most importantly that Chinese companies will be able to win over the consumers with their commitment to high quality and workmanship.
But the economic base for these capabilities is steadily declining.
She said: 'On a scale of one to 10, I feel I'm at a nine because there's definitely room for improvement. I know I could go further.'
《临床心理学》在2012年刊登的一篇研究文章中凸显了设身处地的作用。不管当事人有没有记忆方面的问题,这个方法都能够提高他们的提高记忆能力。和其他针对人类记忆的研究一样,科学家们要求参与者们记忆一个关于人格特点的单词表。参与者被要求使用特定的、能够帮助他们回忆的方法。比如有些参与者用谐音记忆,有些联想这个特征的定义,有一些则用“设身处地法”,把自己想象成那么一个人。
玛莎·切利取出嘴里的香烟,喃喃低语:"我也曾经这么想过。"说完便又抽起了烟。马克震惊了(我们想象一下,当知道你的亲生母亲可能会在你沐浴时杀了你,这反应很正常)。马克第一次意识到家庭主妇会变得多么绝望和孤独。接着,他就想到这会是电视剧的一个好素材。这次谈话便开启了《绝望主妇》的制作。

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

当年秋天开学后,达洛伊西奥开始感觉到肩上背负起了来自投资方的巨大压力。他需要改善软件的运算法则,于是他找到了以色列一个从事自然语言处理的编程团队,并签订了合同。他还用谷歌(Google)搜索找到了一位居住在泰国、在该领域有过重要著作的退休教授。达洛伊西奥说,他成了我们的科研主管,他现在在雅虎的森尼维尔办公室工作。
比蒂在后台说:“这真是我遇到的最离奇的一糟事。感谢上帝!幸好是我们两个人在那里!”
Actively expanding China's opening up to the world

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

2015年最需要迎头赶上的品牌:由于产品线陈旧,大众今年的销量下降了11%,影响了费迪南德o皮切的“称霸全球”计划。沃尔沃的销量则下跌了17%,自从被中国车企收购后,该公司至今还没有任何进步。
8. It’s never too late to start.

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

China will remain an important engine for world growth amid sluggish global economic recovery.
对于韩国部署萨德的决定,中国政府已经以越来越大的愤怒加以回应。尽管韩国坚称该系统旨在保护韩国免受朝鲜导弹的打击,中国却担心该技术会令这个美国的盟国查探中国的军事动向。
6. 查理兹-塞隆 1650万美元

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

4.闻疾病的鼻子
The report found that students majoring in art, agriculture and engineering were more willing to start businesses, while those majoring in history and science showed relatively low interest.
[ai'dentiti]

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

The Southwestern African country owns over 20 national parks and has the world's oldest deserts.

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

adv. 严格地

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

The 1.48 million people who qualified to take the exam marked an increase of 90,000 over last year, while the number of positions offered - 27,000 - remained almost the same.
"Forty percent of Donald Trump's fortune is tied up in Trump Tower and eight buildings within one mile of it," according to the magazine. "What happens in that micromarket does more to affect the net worth of Donald Trump than anything else in the world. Lately, the neighborhood has been struggling (relatively speaking)."

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

看起来,数据造假会在官方层面得到宽容。公布真实数据会把你送上法院的被告席。如果还有更多这类情况发生,公众不再信任官方统计数据将是正确的。
Premiered in August, the 48-episode TV series is a fictional story, with a plot centering on struggles and romance during the Qin Dynasty (221-206 BC).
2014届大学毕业生工作半年后,平均月收入为3487元,较2013届的3250元、2012届的3048元有了较大增长。
二十多年的旨在减少温室气体排放增长的全球谈判几乎没有进展。但在2014年,人们看到了针对这个问题的大规模政治行动的迹象,在30多万人去年九月在纽约举行大游行之后,世界各地的其他城市中也有数以万计的人走上街头。

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

People promoting driverless cars, the most hyped industry segment of the moment, became world leaders in verbiage. Elon Musk claimed to be “laser-focused on achieving full self-driving capability on one integrated platform with an order of magnitude greater safety than the average manually driven car” (ie Tesla cars must stop crashing).
结果发现,被要求画出单词的参与者能够更准确地记起这些单词。而且画本身的质量并不会对记忆效果有什么影响,帮助记忆的仅仅是“画画”这个动作。对于香蕉,画一个大概的轮廓和详细的画出每个细节,产生的作用是一样的。参与者们即使只是花上几秒来画画,也能在记忆结果上有显著提高。研究人员还计划进一步地引进更复杂的单词甚至观点表述来观察参与者记忆表述的准确度。

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

自从2010年开通运营以来,12306票务系统已多次升级以修复漏洞,并在春运期间提供更好的服务。
[?'fekn]

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

北韩已经警告过Park,如果电影穿越边境,将会要他"以命偿罪"。

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

Copestake said fears over economic austerity and the stability of the euro had pushed the index of euro zone cities down in the past year while the inclusion of Caracas was due to artificially high exchange rate controls.
While Cousins' volatile personality and high-usage tendencies present challenges, there are numerous justifications for rolling the dice:
announced
Beijing ranked No 3 on the list of top 10 most congested cites in China, following Jinan and Harbin, according to a report by China Academy of Transportation Sciences.

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

8.Wheel Skates
伦敦博蒙特·内森顾问公司(Beaumont Nathan)的联合创始人雨果·内森(Hugo Nathan)说:“新投资者对早期绘画大师的作品有兴趣,不过他们想要的是杜维恩(Duveen)卖给强盗大亨们的作品。他们想要名作。”他指的是英国艺术交易商约瑟夫·杜维恩(Joseph Duveen),他把很多伟大的艺术品带去了美国。

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

German Three:Mercedes-Benz begins to sag as new lower-priced Benz’s inevitably erode its once invincible “the best or nothing” status. At BMW, imminent arrival of a new 7-series cements its status as the preferred brand of Scarsdale, Shaker Heights, and Santa Monica. A new A3, starting at $30, 795, should nicely lift Audi’s sales beyond 2014’s 15% climb, and a new Q7 SUV should nicely lift profits.
[si'lebriti]
Girls Trip

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

“LBS has broadened my profession horizons and opened international career opportunities,” said one graduate. He added: “In the three years after graduation I have worked in the US, Canada and Hong Kong, while rotating in different businesses from corporate banking to debt capitalmarkets”.
每一次我们詹姆斯已经达到了顶点,詹姆斯就会拿出更好的表现超过那个顶点。他那无所不包的各项技巧,是詹姆斯辛苦训练的证明。你可以嘲笑他所提发布的所有Instagram录像,但这些都是他仍然能够做到这一点的真正原因;詹姆斯从来不轻视他的每一场比赛,一次都没有。结果便是晚上一次又一次无可比拟的表演。
这是乔布斯从2000年6月到2008年9月的照片合集,显示了他健康状况的巨大变化。

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

“老实说,我真的不担心。”科比说,“我的投篮会变好的。”
As China's economic structure evolves, the rich list also is changing.

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
From the themed collection: 家具业回暖明显 将迎销售大年
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

亲爱的朋友,你们即将毕业,呈现在你面前的世界拥有美好的前景和潜力;这个世界并不仅仅以办公室走廊或华尔街的形式出现,而是令人激动不已的真实世界,充满许多未解之谜,以及让人陶醉的体验。我们当中许多人都忽略了这个简单的真理。
['di:li?]
The statement said: "We sincerely apologize to Moonlight, La La Land, Warren Beatty, Faye Dunaway, and Oscar viewers for the error that was made during the award announcement for Best Picture."

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

【编辑语】应聘时必须面对HR,工作期间可能需要HR,离职时还是离不开HR。HR是公司中最深谙职场秘密的部门。以下的18条评论是来自于美国各知名公司的HR或是专业人力资源机构的讲师,其中包括知名作家,前人力资源经理Cynthia Shapiro(《企业机密:50条公司不会告诉你的秘密》一书的作者)。我们一起来了解下吧。
“We weren’t looking to throw the bums out, as they might say about an election. We were just really impressed with a flood of new powertrains, ” says Drew Winter, WardsAuto World Editor-in-Chief. “What was great yesterday might be less impressive tomorrow because engine technology is changing so rapidly.”

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
From the themed collection: 详谈瓷砖美缝未来发展趋势及走势
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

circulate
8.Please aid the Olympic authorities and organisers by demonstrating at all times that you are not a terrorist. Do not perspire, take off your shoes, smile in a weird way while texting someone, or point and shout: "Hey! Look at all those missiles on that roof over there!" In fact, if you're not using your hands for anything, it's probably best if you keep them in the air where everybody can see them.
Collins grew up in rural, apartheid-era South Africa in the 1970s. Her childhood inspired her to focus on empowering women living below the poverty line through grassroots efforts. The Wonderbag, which was inspired by watching her grandmother cook with cushions, uses heat retention technology to cook food for 8-12 hours without the need for additional fuel. Collins witnessed the benefits African women received from using Wonderbags, reducing the amount of time they spent collecting firewood. For every bag sold, another is donated to a household in Africa, and in the past four years, the Wonderbags have found themselves in 600,000 African homes. Collins has launched the Wonderbag in the U.S. on Amazon, and hopes to sell the products via other retailers by 2014.

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

单词stroke 联想记忆:

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

为了解决上述问题,报告建议应尽快制定电子商务法。同时,该报告还呼吁应建立一个在线信用体系,以此加强对电子商务行业的纪律监督。
adj. 暂时的,临时的

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
From the themed collection: 北京加大保障性住房建设力度
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

"绝望主妇"伊娃与老公的性感广告宣传照
n. 释放,让渡,发行

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

然而,时间较长似乎并不代表学业较轻松。要保持学习劲头,合理的时间管理至关重要。英国华威商学院的一名毕业生谈到:“几个必修项目会帮助你跟上进度并避免在最后阶段非常紧张。”总的来说,2012级毕业生花了两年半多一点的时间完成学业。
Perhaps just as important, stable or falling prices will boost the inflation-adjusted pay of U.S. workers and gives them more bang for their buck. "It's an unambiguous positive for household demand," said Neil Dutta, head of economics at Renaissance Macro Research. "People will have more money to spend."

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

愿新年的烛光带给你祥和与喜悦,祝你新年充满爱。
"Pandas used to be really difficult to breed in captivity, but the Chengdu base and other zoos around the world have cracked the problem and now there are around 400 in captivity," Mr Marven said.

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

The result has been increased ratings this regular season. Everything has been flipped. The offseason is thrilling, "stay on your phone every second checking what's happening" drama. The regular season is fascinating and competitive, with superstar matchups and explosive performances every night. The playoffs? Ho-hum, the Warriors win again. What's interesting is that this might be an actually better growth strategy for the league. A dynamite dynasty to attract the casual viewers who only want to see greatness, a super-compelling offseason and intriguing regular season to keep the die-hards engaged. It flips the standard models on their heads, but it also makes the best use of the NBA's ever-expanding digital presence.

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

过去十年中,只有3颗10克拉级且硬度相当的鲜彩蓝钻被拍卖,3颗都未达到12克拉,而且有瑕疵。
今年9月,该指数曾跌至48这个创纪录低点,10月份该读数则为49.9。
在科技初创公司大会上(比如去年12月在赫尔辛基举办的Slush),各方都在讨论体验。未来一年可能会看到更广泛地采用虚拟实境(VR,让用户置身于数字化强化的环境中)和强化实境(AR,把数字信息叠加到现实世界中)来创建新的数字企业。
Apple tops the list of World's 500 Most Influential Brands for 2016, compiled by New York-based World Brand Lab and released last Monday.

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

彭博(Bloomberg)的调查分析此前预计1月份中国CPI应上升1.9%。

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

Age: 45
“We will see a lot of headlines about [emerging market export growth] picking up in the first half of 2017,” says Bhanu Baweja, head of EM cross asset strategy at UBS, who believes EM exports will show year-on-year growth of between 8 and 13 per cent in dollar terms in the first quarter of this year, “a complete postcode away” from the negative numbers currently being reported.
Mr Baweja agrees with this conclusion, noting that both South Korea and India, another net commodity importer, are exporters of refined oil products, the dollar value of which should rise this year.

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

n. 安装,放置,周围,环境,(为诗等谱写的)乐曲
不过巴蒂表示,中国大学排名的稳定并不值得担忧。他说:“数十年的持续投资建设以及中国高等教育国际化程度的提高,无疑将使得中国的大学变得越来越好。”

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

The M3 tomb also "consists of a burialmound, ramp, sealed gate, tomb entrance, screen walls, passage, burial chamberand side chamber" the researchers wrote in a report published recently inthe journalChinese Cultural Relics.
其他两家手机制造商OPPO和vivo的增长率都超过了100%,在2016年分别出货9940万台和7730万台。

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
From the themed collection: 整体配套化日益成为卫浴行业主流
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

Buyers looking for new construction will have more options next year, as the number of new condos hitting the market in Manhattan, Brooklyn and Long Island City, Queens, is expected to more than double to 8,366 from 3,444 in 2014, according to data provided by Corcoran Sunshine Marketing Group.

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

Enrollment: NA
As fall arrived and school began, D'Aloisio felt immense pressure to deliver for his backers. He needed to whip his algorithm into better shape, so he contracted a team of Israeli coders who specialize in natural language processing. Searching on Google, he found and hired a retired professor living in Thailand who'd written seminal books on the topic. 'He became our main scientist,' says D'Aloisio. 'He now works at Yahoo! in the Sunnyvale office.'
每次我跟人说起“未来”,我都被他们对“未来是可知”的这一想法吓到。我的印象就是,大部分人都想象未来像书本一样,有一个结局:已经写好了、也可以读取。你只要快速地窥一眼这本书的最后几页就能知道。他们很难接受这最后几页根本没有写完。未来还没有发生、也没有计划好——也无法预知,因为它们还根本不存在。

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
Paper

Length-scale dependence of protein hydration-shell density

但是他们摆烂的原因还是各不相同的。比如热火队,他们试图通过输球来锻炼队中的年轻人并且确立一个核心;比如魔术队,他们试图摆脱停滞不前的过程。
['t?ɑ:t?]
蒋依依说,2013年人民币兑美元汇率上涨近3%,使北京成为了一个更加昂贵的旅游目的地。
romantic

Graphical abstract: Length-scale dependence of protein hydration-shell density
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

第五步 帅到没朋友
Tracey and Viv Williams, a British couple, dressed as the green cartoon ogres from Shrek at their wedding held recently. Tracy, 33, made a lovely Princess Fion

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

在中国北方分析出的这种病毒与1957年以前传播的病毒相似,因此,1957年以前出生的人一般都有了抵抗力,而在那年之后出生的儿童和年轻人由于没有预先的免疫力而缺乏抵抗力。1978年这种病毒在世界各地传播开来,其中包括美国。这种病主要发生在孩子们身上,因此,这次流感没被看成是真正的大流行。1977-78年的流感季节,还没有及时地生产出控制病毒的疫苗,但是,1978-79年的流感疫苗就包含了这种病毒的疫苗。
平均工作经验:12个月
IT/通信/电子/互联网行业的应届生签约最高月薪为4867元,同比去年下降826元;紧随其后的是金融业和交通/运输/物流/仓储行业,平均签约月薪分别是4692元和4457元。

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
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China in 2012: fixated on stability as the pressures mount without and within.
mortality

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